Multiple populace-built education and you will observational studies have shown you to oophorectomy is actually relevant that have an elevated chance of colorectal disease (CRC), and you can hormones replacement for treatment might have been for the a reduction in the possibility of colorectal cancer tumors. This research was carried out to analyze if hysterectomy, that could impact the levels of women hormone, are for the a risk of disease of specific intestinal system.
Actions
It population-centered retrospective cohort study are conducted playing with insurance coverage analysis available with the medical Insurance rates Review and you can Research Solution (HIRA) regarding . The fresh new hysterectomy classification included forty- in order to 59-year-old ladies who undergone hysterectomy that have uterine leiomyoma otherwise uterine endometriosis away from . The newest control group provided feminine aged 40 so you’re able to 59 many years whom decided to go to scientific organizations to have medical examination out-of .
Performance
The hysterectomy and low-hysterectomhy communities made up 66,204 and you may 89,768 victims, respectively. The latest average many years about low-hysterectomy classification and you will hysterectomy group were forty eight (range: 43–53) and you will 46 (range: 44–49) many years, respectively. Regarding the unadjusted outcome of the research, all colorectal cancers (CRC) increased regarding the hysterectomy by yourself classification (Hours 1.222, 95% believe interval (CI) step 1.0step one6–1.47, p = 0.033), sigmoid cancer of the colon increased from the hysterectomy by yourself class (Time 1.71, 95% CI step one.073–dos.724, p = 0.024), and you may rectal cancers enhanced throughout the hysterectomy having adnexal businesses classification (Hours 1.924, 95% CI step one.073–dos.724, p = 0.002).ادامه خواندن